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Sarah Blossom, Ph.D.

Picture of Picture ofSarah  Blossom
  • Assistant Professor, College of Medicine, Department of Microbiology & Immunology
  • Associate Professor, College of Medicine, Department of Pediatrics


  • Birth Defects Research


  • Basic Scientist

Contact Information

  • Email:
    Phone: 501-364-2861
    Fax: 501-364-3599
    Address: Arkansas Children's Hospital
    1 Children's Way
    Little Rock, AR 72202


  • Ph.D., Univ Of Arkansas For Med Sci, 1999
  • B.S., University of Arkansas, 1991


  • Postdoctoral Fellow, Immunotoxicology, Univ Of Arkansas For Med Sci, 2003-2004

Recent Publications

  • Journal Article, Gilbert KM., Blossom SJ., Erickson SW., Reisfeld B., Zurlinden TJ., Broadfoot B., West K., Bai S., Cooney CA. Chronic exposure to water pollutant trichloroethylene increased epigenetic drift in CD4+ T cells. Epigenomics 2016 May; 8(5):633-49.
  • Journal Article, Blossom SJ., Melnyk SB., Ming L., Wessinger WD., Cooney CA. Inflammatory and oxidative stress-related effects associated with neurotoxicity are maintained after exclusively prenatal trichloroethylene exposure.. NeuroToxicology 2016 January; Epub
  • Journal Article, Gilbert, KM., Reisfeld, B., Zurlindin, T., Kreps, MN., Erickson, SW., Blossom SJ. Modeling toxicodynamic effects of trichloroethylene on liver in mouse model of autoimmune hepatitis. Tox. Appl. Pharmacol. 2014 September 15; 279(3):284-293.
  • Journal Article, Blossom SJ., Rau, JL., Best, TH., Bornemeier, RA., Hobbs, CA. Increased maternal cytokine production and congenital heart defects.. J Reprod Immunol. 2013 April; 97 (2):204-10.
  • Journal Article, Blossom SJ., Cooney, CA., Melnyk, SB., Rau, JL., Swearingen, CA., Wessinger, WD. Metabolic changes and DNA hypomethylation in cerebellum are associated with behavioral alterations in mice exposed to trichloroethylene postnatally. . Toxicol. Appl. Pharmacol. 2013 June 15; 269(3):263-69.
  • Journal Article, Blossom, SJ., Melnyk, S., Cooney, CA., Gilbert, KM., James, SJ., Blossom S. Postnatal Exposure to trichloroethylene alters glutathione redox homeostasis, methylation potential, and neurotrophin expression in the mouse hippocampus. Neurotoxicology 2012 December; Epub 2012 Mar 7(33 (6)):1518-27.
  • Journal Article, Gilbert, KM., Nelson, AR., Cooney, CA., Reisfeld, B., Blossom, SJ. Epigenetic Alterations may regulate temporary reversal of CD4 T cell activation caused by trichloroethylene exposure. Tox. Sci. 2012 May; 127(1):169-78.
  • Journal Article, Gilbert, KM., Rowley, B., Gomez-Acevedo, H., Blossom, SJ. Co-exposure to HgCl2 increases immunotoxicity of trichloroethylene. Toxicol. Sci. 2011 February; 119(2):281-292.
  • Journal Article, Gilbert, K.M., Przybyla, B., Pumford, N.R., Han, T., Fuscoe, J., Schnackenberg, L.K., Holland, R.D., Doss, J.C., Macmillan-Crow, L.A., Blossom, S.J. Delineating liver events in trichloroethylene-induced autoimmune hepatitis. Chem. Res. Toxicol. 2009. April 22; 4:626-632.
  • Journal Article, James, S.J., Rose, S., Melnyk, S., Jernigan, S., Blossom, S., Pavliv, O., Gaylor, D.W. Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism. FASEB J. 2009 Aug; 23(8):2371-83.

Recent Grant Awards

  • CD4+T Cell-mediated Neurotoxicity with Continuous Trichlorethylene Exposure, NIH, 1K02ES024387-01, 2014-09-10 00:00:00-2019-08-31 00:00:00
  • CD4+T Cell-mediated Neurotoxicity with Continuous Trichlorethylene Exposure, NIH, 1K02ES024387-02, 2014-09-10 00:00:00-2019-08-31 00:00:00
  • CD4+T Cell-mediated Neurotoxicity with Continuous Trichlorethylene Exposure, NIH, 1K02ES024387-03, 2014-09-10 00:00:00-2019-08-31 00:00:00
  • Developmental Programming of Trichloroethylene (TCE)-induced Autoimmune Disease, NIH, 4R01ES021484-04, 2012-12-01 00:00:00-2017-10-31 00:00:00

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