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Mario A. Cleves, Ph.D.

Picture of Picture ofMario A. Cleves
  • Professor, College of Medicine, Department of Pediatrics
  • Professor, College of Public Health, Department of Biostatistics
  • Professor, College of Medicine
  • Section Chief, Biostatistics


  • Biostatistics


  • Biostatistics

Contact Information

  • Email:
    Phone: 501-364-5033
    Fax: 501-364-3947
    Address: Arkansas Children's Hospital
    1 Children's Way
    Little Rock, AR 72202


  • Universidad de Los Andes, 1978
  • B.S., University of Oklahoma Health Sciences Center, 1980
  • M.S., University of Oklahoma Health Sciences Center, 1983
  • Ph.D., University of Oklahoma Health Sciences Center, 1992


  • Post-Doc, Statistical Genetics, Case Western Reserve University, 1995-1997

Licensure and Board Certification

  • American Society for Clinical Pathology, Medical Technologist (MT)

Clinical & Research Interests

  • Basic Science, Clinical Research, Translational Research

Recent Honors

  • Charles C. Shepard Science Award Assessment and Epidemiology, U.S. Department of Health and Human Services Centers for Disease Control and Prevention Agency for Toxic Substances and Disease Registry, 2009
  • Associate Director Center of Birth Defects Research and Prevention, UAMS College of Medicine, 2009
  • International Genetic Epidemiology Society, Publication Committee, 2010

Recent Publications

  • Journal Article, Ou X,Andres A,Pivik RT,Cleves MA,Snow JH,Ding Z,Badger TM Voxel-Based Morphometry and fMRI Revealed Differences in Brain Gray Matter in Breastfed and Milk Formula-Fed Children. AJNR Am J Neuroradiol 2016 Apr 37 (4): 713-9.
  • Journal Article, Ronis MJ,Gomez-Acevedo H,Blackburn ML,Cleves MA,Singhal R,Badger TM Uterine responses to feeding soy protein isolate and treatment with 17beta-estradiol differ in ovariectomized female rats. Toxicol Appl Pharmacol 2016 Apr 15 297 68-80.
  • Journal Article, Yeruva L,Spencer NE,Saraf MK,Hennings L,Bowlin AK,Cleves MA,Mercer K,Chintapalli SV,Shankar K,Rank RG,Badger TM,Ronis MJ Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model. BMC Gastroenterol 2016 16 40.
  • Journal Article, Mercer KE,Pulliam C,Hennings L,Lai K,Cleves M,Jones E,Drake RR,Ronis M Soy Protein Isolate Protects Against Ethanol-Mediated Tumor Progression in Diethylnitrosamine-Treated Male Mice. Cancer Prev Res (Phila) 2016 Jun 9 (6): 466-75.
  • Journal Article, Li M,Li J,He Z,Lu Q,Witte JS,Macleod SL,Hobbs CA,Cleves MA Testing Allele Transmission of an SNP Set Using a Family-Based Generalized Genetic Random Field Method. Genet Epidemiol 2016 May 40 (4): 341-51.
  • Journal Article, Pettey CM,McSweeney JC,Stewart KE,Cleves MA,Price ET,Heo S,Souder E African Americans' Perceptions of Adherence to Medications and Lifestyle Changes Prescribed to Treat Hypertension. Sage Open 2016 Jan-Mar 6 (1):.
  • Journal Article, Ronis MJ,Gomez-Acevedo H,Blackburn ML,Cleves MA,Singhal R,Badger TM RNA-sequencing data analysis of uterus in ovariectomized rats fed with soy protein isolate, 17beta-estradiol and casein. Data Brief 2016 Jun 7 1491-6.
  • Journal Article, Li M,He Z,Schaid DJ,Cleves MA,Nick TG,Lu Q A powerful nonparametric statistical framework for family-based association analyses. Genetics 2015 May 200 (1): 69-78.
  • Journal Article, Pivik RT,Andres A,Tennal KB,Gu Y,Cleves MA,Badger TM Infant diet, gender and the development of vagal tone stability during the first two years of life. Int J Psychophysiol 2015 May 96 (2): 104-14.
  • Journal Article, Andres A,Moore MB,Linam LE,Casey PH,Cleves MA,Badger TM Compared with feeding infants breast milk or cow-milk formula, soy formula feeding does not affect subsequent reproductive organ size at 5 years of age. J Nutr 2015 May 145 (5): 871-5.

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